The quasi-parallel lives of satellite cells and atrophying muscle.

摘要: Skeletal muscle atrophy or wasting accompanies various chronic illnesses and the aging process, thereby reducing function. One of most important components contributing to effective repair in postnatal organisms, satellite cells (SCs), have recently become focus several studies examining factors participating atrophic process. We critically examine here experimental evidence linking SC function with loss connection diseases as well aging, subsequent recovery Several recent reports investigated changes SCs terms their differentiation proliferative capacity response stimuli. In this regard, we review molecular within that contribute dysfunctional status atrophy, intention shedding light on novel potential pharmacological targets counteract mass.