作者: S.B. Hladky , D.A. Haydon
DOI: 10.1016/S0070-2161(08)60444-X
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摘要: Publisher Summary This chapter discusses gramicidin with respect to its structure and why it is believed be a channel. The gramicidins, of which there are several, linear 15-amino acid polypeptides produced by Bacillus hreuis. naturally occurring mixture A, B, C in the approximate ratio 72 : 9 1. primary A unusual several respects. One properties that has greatly facilitated study readily measurable single-channel conductance duration. Unlike conductance, both frequency opening channels mean channel open time or duration strong functions membrane lipid. also gramicidins regard stability kinetics formation decomposition lipid membranes relation ion water permeability.