PD-1 blockade induces responses by inhibiting adaptive immune resistance

作者: Paul C. Tumeh , Christina L. Harview , Jennifer H. Yearley , I. Peter Shintaku , Emma J. M. Taylor

DOI: 10.1038/NATURE13954

关键词:

摘要: … margin and inside tumours, with close proximity between PD-1 and PD-L1, and a more … PD-1 blockade requires pre-existing CD8 + T cells that are negatively regulated by PD-1/PD…

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