Extended pelvic resections for recurrent or persistent uterine and cervical malignancies: an update on out of the box surgery.

摘要: Abstract Objective To update our report on the outcome of patients who underwent extended pelvic resection (EPR) for recurrent or persistent uterine and cervical malignancies. Methods We reviewed records all EPR between 6/2000 07/2011. was defined as an en-bloc a tumor with sidewall muscle, bone, major nerve, and/or vascular structure. Complications up to 180 days post surgery were analyzed. Survivals estimated using Kaplan–Meier method. Results identified 22 patients. Median age at time 58 years (range, 36–74). diameter 5.4 cm 1.5–11.2). Primary sites included: uterus, 13; cervix, 7; synchronous uterus/cervix, 1; uterus/ovary, 1. The structures were: 10; 8; vessel, 5. Complete gross microscopically negative margins (R0 resection) achieved in 17 (77%). There no perioperative mortalities. Major postoperative complications occurred 14 (64%). two most common morbidities abscesses peripheral neuropathies. follow-up 28 months 6–99). 5-year overall survival (OS) entire cohort 34% (95% CI, 13–57). For had R0 resection, OS 48% 19–73). In positive pathologic (n = 5), 0%. Conclusion associated prolonged when achieved. high rate remains hallmark these procedures properly selected should be extensively counseled preoperatively.