Soft tissue aspiration cytopathology.

摘要: BACKGROUND Fine-needle aspiration (FNA) biopsy as a diagnostic modality for the pathologic evaluation of soft tissue neoplasms and non-neoplastic mass lesions is uncommon controversial. This procedure contrasts with more traditional methods such marginal excision, incisional (open) biopsy, or even core to procure from somatic sites. METHODS The authors reviewed results cytopathologic diagnoses obtained by fine-needle over consecutive 11-month period in patients that presented primarily palpable mass. A few deep non-palpable masses also were evaluated radiologically guided FNA. Cytopathologic verified different means including examination either concurrent cell block subsequent surgical flow cytometry, clinical outcome, repetition FNA procedure. Patients followed minimum one year evaluate clinically, determine whether any further therapy was administered, assess disease status. RESULTS Eighty-two aspirates performed without complications 77 ranging 12–88 years age (mean = 50 yrs.) men outnumbering women 1.5:1. Soft most common extremities (41 cases), trunk (34 retroperitoneum (5 head neck (2 cases). Fine-needle diagnosed malignant 42 (51%), benign 32 (39%), nondiagnostic 6 (7%), atypical 2 (2%) cases. Malignant comprised 24 sarcomas (57%), 9 carcinomas (21%), lymphomas (14%), 3 melanomas (7%). Twenty-two (52%) had an initial diagnosis malignancy, whereas 18 (43%) represented metastatic (5%) recurrent neoplasms. Confirmation 57%, cytometry 5%, outcome 34%, repeat 4%. One false negative no positive issued sensitivity specificity 100% 97% respectively distinguishing Of aspirates, 83% could be subtyped 72% correctly subtyped. For primary sarcomas, 12 19 (63%) accurately In 48% cases found diagnostically useful 54% them. CONCLUSIONS Aspiration cytopathology using can accurate minimally invasive method masses, confirmation tumors tissue, documentation locally capable specifically subtyping large percentage if cellular material form addition smears. Cancer (Cancer Cytopathol) 2000;90:292–8. © 2000 American Society.