Coronary vasodilator capacity and epicardial vessel remodeling in physiological and hypertensive hypertrophy.
作者： Michaela Kozàkovà , Fabio Galetta , Luisa Gregorini , Giovanni Bigalli , Ferdinando Franzoni
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摘要: Abstract —The aim of this study was to compare resting coronary flow velocity, determinants myocardial oxygen demand, and vasodilator capacity in subjects with physiological, exercise-induced, hypertensive left ventricular hypertrophy. Sixteen healthy sedentary men, 16 endurance athletes, (mean±SEM for mass index: 94.9±5.5, 184.6±8.4, 154.4±9.5 g/m 2 , respectively) were studied by transesophageal transthoracic Doppler echocardiography. Coronary velocity anterior descending artery cross-sectional area main assessed at rest during dipyridamole-induced vasodilation. Myocardial demand estimated through rate-pressure product, wall stress, inotropic function. reserve minimum resistance comparable those men athletes (mean±SEM: 3.23±0.16 versus 3.60±0.18 0.96±0.06 1.04±0.04 mm Hg · s cm − 1 ), while they decreased increased, respectively 2.31±0.08 1.21±0.10 ; P
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