C-H Bond Cleavage by Bioinspired Nonheme Oxoiron(IV) Complexes, Including Hydroxylation of n-Butane.

摘要: The development of efficient and selective hydrocarbon oxidation processes with low environmental impact remains a major challenge the 21st century because strong apolar nature C–H bond. Naturally occurring iron-containing metalloenzymes can, however, selectively functionalize bonds on substrates under mild environmentally benign conditions. key oxidant in number these transformations is postulated to possess an S = 2 FeIV═O unit nonheme ligand environment. This has been trapped spectroscopically characterized its reactivity toward demonstrated for several iron enzyme classes. In order obtain insight into structure–activity relationships reactive intermediates, over 60 synthetic FeIV(O) complexes have prepared various laboratories their reactivities investigated. Forum Article summarizes current status efforts characterization bond cleavage syn...