作者: Jerry Ware , Shashank Jain
DOI: 10.1016/B978-0-12-387837-3.00038-9
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摘要: The platelet/tumor cell interaction points to another example supporting the multi-functional properties of platelet. Long recognized as central players in hemostasis and thrombosis, platelets can be essentially hijacked participate a wide range pathological events tumor growth spread cells. platelet particularly advantageous storing cytokines factors that normally support fundamental role wound repair. However, cancer setting these same angiogenesis giving distinct advantage cell. Decades effort understand biology thrombosis has positioned studies provide key mechanistic insights biology. In addition, this work is identifying previously untested therapeutic targets for management tumorigenesis malignancy. Ultimately, outcomes from efforts may improve prognosis patient.