Novel regulatory mechanism in human urinary bladder: central role of transient receptor potential melastatin 4 channels in detrusor smooth muscle function

作者: Kiril L. Hristov , Amy C. Smith , Shankar P. Parajuli , John Malysz , Eric S. Rovner

DOI: 10.1152/AJPCELL.00270.2015

关键词:

摘要: Transient receptor potential melastatin 4 (TRPM4) channels are Ca2+-activated nonselective cation that have been recently identified as regulators of detrusor smooth muscle (DSM) function ...

参考文章(51)
R Guinamard, T Hof, C A Del Negro, The TRPM4 channel inhibitor 9-phenanthrol British Journal of Pharmacology. ,vol. 171, pp. 1600- 1613 ,(2014) , 10.1111/BPH.12582
Sarah K Burris, Qian Wang, Simon Bulley, Zachary P Neeb, Jonathan H Jaggar, 9‐Phenanthrol inhibits recombinant and arterial myocyte TMEM16A channels British Journal of Pharmacology. ,vol. 172, pp. 2459- 2468 ,(2015) , 10.1111/BPH.13077
Shankar P Parajuli, Kiril L Hristov, Rupal P Soder, Whitney F Kellett, Georgi V Petkov, NS309 decreases rat detrusor smooth muscle membrane potential and phasic contractions by activating SK3 channels British Journal of Pharmacology. ,vol. 168, pp. 1611- 1625 ,(2013) , 10.1111/BPH.12049
A. Conte, A. Giannantoni, S. Proietti, S. Giovannozzi, G. Fabbrini, A. Rossi, M. Porena, A. Berardelli, Botulinum toxin A modulates afferent fibers in neurogenic detrusor overactivity European Journal of Neurology. ,vol. 19, pp. 725- 732 ,(2012) , 10.1111/J.1468-1331.2011.03618.X
C J Garland, S V Smirnov, P Bagher, C S Lim, C Y Huang, R Mitchell, C Stanley, A Pinkney, K A Dora, TRPM4 inhibitor 9-phenanthrol activates endothelial cell intermediate conductance calcium-activated potassium channels in rat isolated mesenteric artery. British Journal of Pharmacology. ,vol. 172, pp. 1114- 1123 ,(2015) , 10.1111/BPH.12985
Ralf Fliegert, Günter Glassmeier, Frederike Schmid, Kerstin Cornils, Selda Genisyuerek, Angelika Harneit, Jürgen R. Schwarz, Andreas H. Guse, Modulation of Ca2+ entry and plasma membrane potential by human TRPM4b FEBS Journal. ,vol. 274, pp. 704- 713 ,(2007) , 10.1111/J.1742-4658.2006.05614.X
Yosuke Kaneko, Arpad Szallasi, Transient receptor potential (TRP) channels: a clinical perspective. British Journal of Pharmacology. ,vol. 171, pp. 2474- 2507 ,(2014) , 10.1111/BPH.12414
Ann T. Hanna-Mitchell, Mandavi Kashyap, Wilson Ventura Chan, Karl-Eric Andersson, Cara Tannenbaum, Pathophysiology of idiopathic overactive bladder and the success of treatment: A systematic review from ICI-RS 2013 Neurourology and Urodynamics. ,vol. 33, pp. 611- 617 ,(2014) , 10.1002/NAU.22582
Christopher R. Chapple, Linda Cardozo, Victor W. Nitti, Emad Siddiqui, Martin C. Michel, Mirabegron in overactive bladder: A review of efficacy, safety, and tolerability Neurourology and Urodynamics. ,vol. 33, pp. 17- 30 ,(2014) , 10.1002/NAU.22505