Liver microsomal electron transport systems: II. The involvement of cytochrome b5 in the NADH-dependent hydroxylation of 3,4-benzpyrene by a reconstituted cytochrome P-448-containing system
作者： Susan B. West , Wayne Levin , Dene Ryan , Mary Vore , Anthony Y.H. Lu
DOI: 10.1016/0006-291X(74)90395-7
关键词:
摘要: Abstract An enzyme system in rat liver microsomes which catalyzes the NADH-dependent hydroxylation of 3,4-benzpyrene has been reconstituted. The essential components this NADH-mediated electron transport chain are cytochrome b5, NADH-cytochrome b5 reductase, lipid, and P-448.
elsevier.com
sci-hub.se 参考文章(13)
Alvah H. Phillips, Robert G. Langdon, Hepatic Triphosphopyridine Nucleotide-Cytochrome c Reductase: Isolation, Characterization, and Kinetic Studies Journal of Biological Chemistry. ,vol. 237, pp. 2652- 2660 ,(1962) , 10.1016/S0021-9258(19)73803-4
W. Levin, D. Ryan, S. West, A.Y.H. Lu, Preparation of Partially Purified, Lipid-depleted Cytochrome P-450 and Reduced Nicotinamide Adenine Dinucleotide Phosphate-Cytochrome c Reductase from Rat Liver Microsomes Journal of Biological Chemistry. ,vol. 249, pp. 1747- 1754 ,(1974) , 10.1016/S0021-9258(19)42851-2
D W Nebert, H V Gelboin, Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture: I. Assay and properties of induced enzyme Journal of Biological Chemistry. ,vol. 243, pp. 6242- 6249 ,(1968) , 10.1016/S0021-9258(18)94484-4
Yoshihiro Miyake, James L. Gaylor, Electron Transfer from α-Reduced Nicotinamide Adenine Dinucleotide to Flavoprotein, Cytochromes, and Mixed Function Oxidases of Rat Liver Microsomes Journal of Biological Chemistry. ,vol. 248, pp. 7345- 7352 ,(1973) , 10.1016/S0021-9258(19)43295-X
Lawrence Spatz, Philipp Strittmatter, A Form of Reduced Nicotinamide Adenine Dinucleotide-Cytochrome b5 Reductase Containing Both the Catalytic Site and an Additional Hydrophobic Membrane-binding Segment Journal of Biological Chemistry. ,vol. 248, pp. 793- 799 ,(1973) , 10.1016/S0021-9258(19)44337-8
A Y H Lu, K W Junk, M J Coon, Resolution of the Cytochrome P-450-containing ω-Hydroxylation System of Liver Microsomes into Three Components Journal of Biological Chemistry. ,vol. 244, pp. 3714- 3721 ,(1969) , 10.1016/S0021-9258(18)83427-5
Alfred Hildebrandt, Ronald W. Estabrook, Evidence for the participation of cytochrome b5 in hepatic microsomal mixed-function oxidation reactions Archives of Biochemistry and Biophysics. ,vol. 143, pp. 66- 79 ,(1971) , 10.1016/0003-9861(71)90186-X
Nozomu Oshino, Yoshio Imai, Ryo Sato, Electron-transfer mechanism associated with fatty acid desaturation catalyzed by liver microsomes Biochimica et Biophysica Acta (BBA) - Enzymology and Biological Oxidation. ,vol. 128, pp. 13- 28 ,(1966) , 10.1016/0926-6593(66)90137-8
Eugene G. Hrycay, Peter J. O'Brien, Microsomal electron transport. I. Reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase and cytochrome P-450 as electron carriers in microsomal NADPH-peroxidase activity. Archives of Biochemistry and Biophysics. ,vol. 160, pp. 230- 245 ,(1974) , 10.1016/S0003-9861(74)80030-5
Yoshiyuki Ichikawa, Joann S. Loehr, NADH-dependent cytochrome P-450 oxidase system in submicrosomal particles Biochemical and Biophysical Research Communications. ,vol. 46, pp. 1187- 1193 ,(1972) , 10.1016/S0006-291X(72)80100-1