Techniques and Kinetics of Hemodiafiltration

作者: Luciano A. Pedrini

DOI: 10.1007/978-3-642-27558-6_5

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摘要: Medium–long-term application of on-line high-efficiency HDF compared to low- and high-flux HD results in enhanced removal lower basal levels small, medium protein-bound uremic solutes, some which are retained as markers or causative agents several derangements, mainly inflammation, secondary hyperparathyroidism, dyslipidemia cardiovascular disease. Probably, many the benefits attributed potentially result from a general reduction toxicity. This might be link with clinical reported patients undergoing chronic eventually contribute improving survival, suggested by published observational studies. However, In absence large randomized, prospective studies, it is reasonable conclude that online logical safe therapy effective maintaining life wellbeing dialysis patients. Knowledge performance materials, apparatus devices used HDF, study solute transport mechanisms aid modelling simulation will help optimize this technique obtain additional benefits.

参考文章(173)
J A Sargent, F A Gotch, Mathematic modeling of dialysis therapy Kidney International. ,vol. 10, ,(1980)
Gotch Fa, Keen M, Prowitt M, Lam Ma, Preliminary clinical results with sodium-volume modeling of hemodialysis therapy. Proceedings of the Clinical Dialysis and Transplant Forum. ,vol. 10, pp. 12- ,(1980)
P. Zucchelli, A. Santoro, Inorganic phosphate removal during different dialytic procedures. International Journal of Artificial Organs. ,vol. 10, pp. 173- 178 ,(1987) , 10.1177/039139888701000308
Luciano A. Pedrini, Simona Zerbi, Mixed-dilution hemodiafiltration. Contributions To Nephrology. ,vol. 158, pp. 123- 130 ,(2007) , 10.1159/000107242
L.W. Henderson, A. Besarab, A. Michaels, L.W. Bluemle, Blood purification by ultrafiltration and fluid replacement (diafiltration) Hemodialysis International. ,vol. 8, pp. 10- 18 ,(2004) , 10.1111/J.1492-7535.2004.00081.X
Natalie Meert, Marie-Anne Waterloos, Maria Van Landschoot, Annemieke Dhondt, Ingrid Ledebo, Griet Glorieux, Jan Goeman, Johan Van der Eycken, Raymond Vanholder, Prospective Evaluation of the Change of Predialysis Protein‐Bound Uremic Solute Concentration With Postdilution Online Hemodiafiltration Artificial Organs. ,vol. 34, pp. 580- 585 ,(2010) , 10.1111/J.1525-1594.2010.01005.X
Nicholas A. Hoenich, Membranes and filters for haemodiafiltration. Contributions To Nephrology. ,vol. 158, pp. 57- 67 ,(2007) , 10.1159/000107235
L.A. Pedrini, V. De Cristofaro, B. Pagliari, M. Filippini, P. Ruggiero, Optimization of Convection on Hemodiafiltration by Transmembrane Pressure Monitoring and Biofeedback Contributions To Nephrology. ,vol. 137, pp. 254- 259 ,(2002) , 10.1159/000060221
M Schulze, J Floege, K M Koch, A Bartsch, S Shaldon, L C Smeby, Clearance and synthesis rates of beta 2-microglobulin in patients undergoing hemodialysis and in normal subjects. Journal of Laboratory and Clinical Medicine. ,vol. 118, pp. 153- 165 ,(1991)