CCL5 Promotes Macrophage Recruitment and Survival in Human Adipose Tissue

作者: Mayoura Keophiphath , Christine Rouault , Adeline Divoux , Karine Clément , Danièle Lacasa

DOI: 10.1161/ATVBAHA.109.197442

关键词:

摘要: … For example, mouse models of obesity have unraveled an important role for CCL2/CCR2 in macrophage accumulation and metabolic complications. Antagonists or deletion of CCR2 …

参考文章(38)
Kengo Furuichi, Ji-Liang Gao, Richard Horuk, Takashi Wada, Shuichi Kaneko, Philip M. Murphy, Chemokine Receptor CCR1 Regulates Inflammatory Cell Infiltration after Renal Ischemia-Reperfusion Injury Journal of Immunology. ,vol. 181, pp. 8670- 8676 ,(2008) , 10.4049/JIMMUNOL.181.12.8670
P.T. Kovanen, E.A. Nikkilä, T.A. Miettinen, Regulation of cholesterol synthesis and storage in fat cells. Journal of Lipid Research. ,vol. 16, pp. 211- 223 ,(1975) , 10.1016/S0022-2275(20)36728-6
Christian Weber, Kim S. C. Weber, Christiane Klier, Songhai Gu, Rudolf Wank, Richard Horuk, Peter J. Nelson, Specialized roles of the chemokine receptors CCR1 and CCR5 in the recruitment of monocytes and TH1-like/CD45RO+T cells Blood. ,vol. 97, pp. 1144- 1146 ,(2001) , 10.1182/BLOOD.V97.4.1144
M Zeyda, D Farmer, J Todoric, O Aszmann, M Speiser, G Györi, G J Zlabinger, T M Stulnig, Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production International Journal of Obesity. ,vol. 31, pp. 1420- 1428 ,(2007) , 10.1038/SJ.IJO.0803632
V. Bourlier, A. Zakaroff-Girard, A. Miranville, S. De Barros, M. Maumus, C. Sengenes, J. Galitzky, M. Lafontan, F. Karpe, K.N. Frayn, A. Bouloumié, Remodeling Phenotype of Human Subcutaneous Adipose Tissue Macrophages Circulation. ,vol. 117, pp. 806- 815 ,(2008) , 10.1161/CIRCULATIONAHA.107.724096
Youhong Hu, Lixin Qiao, Shaomeng Wang, Suo-bao Rong, Emmanuelle J. Meuillet, Margareta Berggren, Alfred Gallegos, Garth Powis, Alan P. Kozikowski, 3-(Hydroxymethyl)-bearing phosphatidylinositol ether lipid analogues and carbonate surrogates block PI3-K, Akt, and cancer cell growth. Journal of Medicinal Chemistry. ,vol. 43, pp. 3045- 3051 ,(2000) , 10.1021/JM000117Y
M. Amine Bouhlel, Bruno Derudas, Elena Rigamonti, Rébecca Dièvart, John Brozek, Stéphan Haulon, Christophe Zawadzki, Brigitte Jude, Gérard Torpier, Nikolaus Marx, Bart Staels, Giulia Chinetti-Gbaguidi, PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties. Cell Metabolism. ,vol. 6, pp. 137- 143 ,(2007) , 10.1016/J.CMET.2007.06.010
Chia-Lin Tsou, Wendy Peters, Yue Si, Sarah Slaymaker, Ara M. Aslanian, Stuart P. Weisberg, Matthias Mack, Israel F. Charo, Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites Journal of Clinical Investigation. ,vol. 117, pp. 902- 909 ,(2007) , 10.1172/JCI29919
Einar E Eriksson, Mechanisms of leukocyte recruitment to atherosclerotic lesions: future prospects Current Opinion in Lipidology. ,vol. 15, pp. 553- 558 ,(2004) , 10.1097/00041433-200410000-00009
Siamon Gordon, Philip R. Taylor, Monocyte and macrophage heterogeneity Nature Reviews Immunology. ,vol. 5, pp. 953- 964 ,(2005) , 10.1038/NRI1733