The Dissemination of Glioma by Extension at a Distance

摘要: The manner of growth and dissemination gliomata constitutes an important study, yet actual information concerning this subject, as such, is scant. general impression that these tumors are infiltrative, they grow more or less symmetrically, in certain types, such the medulloblastoma, occurs by “seeding.” fact may occur otherwise than metastasis was shown a brain harboring pinealoma which recently came under observation. This tumor had spread directly from its original position pineal recess to subependymal layer lateral ventricles. unusual way extension at distance stimulated investigation method dissemination. case reported together with other similar cases found literature order define far possible glioma distance. Report Case M. F. (University Pennsylvania Hosp. No. 29690), boy aged eighteen, admitted service Dr. A. Stengel University Hospital on May 22, 1934. He subsequently studied W. G. Spiller C. H. Frazier. The patient well until two years prior admission, when he developed polydypsia polyuria. These symptoms continued entered hospital. One year entrance marked beginning mental retardation along hypersomnia, easy fatigability, impaired memory for recent events. The pupils were fixed dilated, especially right, there limitation upward associated ocular movements. left external rectus superior oblique muscles partially paralyzed. fundi showed hazy disc margins good color. visual acuity 6/15 O.D. 6/22 O.S. Visual fields irregular defects upper quadrant lower right both sides. There asthenia all extremities, decreased but equal tendon reflexes. body hair distinctly female distribution. basal metabolic rate — 32 per cent 24 cent. Roentgenograms skull definite evidence increased intracranial pressure calcified displaced downward backward. spinal fluid 180 200 mm. water. gradually deteriorated died.