Evidence for the expression and enzymatic activity of haem oxygenase-1 in the lungs of horses
作者： C. A. Wyse , C. Nixon , M. McLaughlin , F. J. Dowell , A. W. Philbey
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摘要: The aim of this study was to characterise the expression haem oxygenase-1 (HO-1) in healthy lung tissue from horses and measure its activity. Samples were collected six euthanased for reasons other than respiratory disease. HO-1 activity detected type II alveolar epithelial cells, macrophages neutrophils all samples examined. dependent on presence NADPH inhibited quantitatively by addition increasing concentrations a competitive inhibitor HO-1, tin mesoporphyrin IX.
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