Genetic Defects of Female Sexual Differentiation
作者： A.B. Dessens , M.B.C.M. Cools , A. Richter-Unruh , L.H.J. Looijenga , J.A. Grootegoed
DOI: 10.1016/B978-008088783-8.00101-7
关键词:
摘要: This chapter provides an outline of what is known about ovarian and female development. Specifically, the question addressed if there are any genes which specifically required for differentiation bipotential gonads to become ovaries. In addition, defects in as a result sex chromosomal mosaicism discussed. Subsequently, various causes maternal fetal androgen excess syndromes reviewed well agenesis uterus vagina forming separate entity within 46,XX disorders development category. Finally, relevant points regarding independent effects genetic factors androgens on brain behavior summarized.
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