The European Prospective Investigation into Cancer and Nutrition (EPIC).

摘要: Objective To describe the main finding produced so far by EPIC project, which aims to improve scientific knowledge of nutritional factors involved in cancer. Design and setting Prospective cohort study 23 centres from 10 European countries. Dietary assessment method varied countries: some cases a diet history personal interview was carried out, while most countries self-administered semi-quantitative food-frequency questionnaire used; one case combined with food record. Information on wide range lifestyle anthropometric measurements were also collected for participants. Subjects The includes 521,468 men women mostly aged between 39 69 years, whereas blood samples are available 387,889 subjects. Results date 24 185 cancer have been identified follow-up cohort. publications each centre can be consulted website (http://www.iarc.fr/epic/). Among initial findings concerning associations dietary factors, important results is protective effect high fibre intake fish consumption against colorectal cancer, red processed meat increase risk. Regarding lung first analyses found fruit but no association vegetable consumption. No observed vegetables risk prostate or breast Finally, data Cambridge point an interesting result regarding cancer: saturated fat measured questionnaire, according diary daily 35 g doubles compared less.