Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration for Lymph Node Staging in Patients with Non-small Cell Lung Cancer in Nonoperable Patients Pursuing Radiotherapy as a Primary Treatment

摘要: Introduction Carbon ion radiotherapy (CIRT) is a promising modality with excellent localization and significant biologic effects on tumors. Nevertheless, success depends primarily accurate staging before radiotherapy. Surgical interventions should be avoided in patients considered for CIRT because they usually have multiple comorbidities. The aim of this study was to evaluate the effectiveness endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) lymph node non-small cell lung cancer CIRT. Methods From April 2005 December 2007, 49 abnormal positron emission tomography-computed tomography (PET-CT) accumulations mediastinum and/or hilum were evaluated by EBUS-TBNA. convex probe EBUS used Results There 38 men 11 women. Their mean age 75.2 years (range: 55–87). Based PET-CT, clinical four N1 disease, 42 N2 three N3 disease. By histology, 26 had adenocarcinoma, 19 squamous carcinoma, other histologies. All positive nodes PET-CT aspirated 1–5; average 2.55 nodes/patient). EBUS-TBNA diagnosed 43 cases as N0 disease result underwent Forty remained stable condition without local recurrences (follow-up 6–46 months). diagnostic accuracy 93.9%. Conclusions offers minimally invasive who are candidates can safely performed high