Nickel-Catalyzed C–H Alkynylation of Anilines: Expedient Access to Functionalized Indoles and Purine Nucleobases

作者: Zhixiong Ruan , Sebastian Lackner , Lutz Ackermann

DOI: 10.1021/ACSCATAL.6B01120

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摘要: C–H alkynylations of electron-rich anilines were accomplished by means of user-friendly nickel catalysis. The C–H functionalization occurred with high positional selectivity and ample …

参考文章(87)
Jeung Gon Kim, Kwangmin Shin, Sukbok Chang, Rh(III)- and Ir(III)-Catalyzed Direct C–H Bond Transformations to Carbon–Heteroatom Bonds Topics in Organometallic Chemistry. ,vol. 55, pp. 29- 51 ,(2015) , 10.1007/3418_2015_123
Zhuo-Zhuo Zhang, Bin Liu, Cai-Yun Wang, Bing-Feng Shi, Cobalt(III)-Catalyzed C2-Selective C-H Alkynylation of Indoles. Organic Letters. ,vol. 17, pp. 4094- 4097 ,(2015) , 10.1021/ACS.ORGLETT.5B02038
Kei Muto, Taito Hatakeyama, Junichiro Yamaguchi, Kenichiro Itami, C-H arylation and alkenylation of imidazoles by nickel catalysis: solvent-accelerated imidazole C-H activation. Chemical Science. ,vol. 6, pp. 6792- 6798 ,(2015) , 10.1039/C5SC02942B
Yan-Hua Liu, Yue-Jin Liu, Sheng-Yi Yan, Bing-Feng Shi, Ni(II)-catalyzed dehydrative alkynylation of unactivated (hetero)aryl C–H bonds using oxygen: a user-friendly approach Chemical Communications. ,vol. 51, pp. 11650- 11653 ,(2015) , 10.1039/C5CC03729H
Vijay Gayakhe, Yogesh S. Sanghvi, Ian J. S. Fairlamb, Anant R. Kapdi, Catalytic C–H bond functionalisation of purine and pyrimidine nucleosides: a synthetic and mechanistic perspective Chemical Communications. ,vol. 51, pp. 11944- 11960 ,(2015) , 10.1039/C5CC03416G
Yoshiaki Nakao, Hydroarylation of alkynes catalyzed by nickel. Chemical Record. ,vol. 11, pp. 242- 251 ,(2011) , 10.1002/TCR.201100023
Yue-Jin Liu, Yan-Hua Liu, Sheng-Yi Yan, Bing-Feng Shi, A sustainable and simple catalytic system for direct alkynylation of C(sp2)–H bonds with low nickel loadings Chemical Communications. ,vol. 51, pp. 6388- 6391 ,(2015) , 10.1039/C5CC01163A
Ilya V. Seregin, Victoria Ryabova, Vladimir Gevorgyan, Direct Palladium-Catalyzed Alkynylation of N-Fused Heterocycles Journal of the American Chemical Society. ,vol. 129, pp. 7742- 7743 ,(2007) , 10.1021/JA072718L
Chao Feng, Daming Feng, Teck-Peng Loh, Rhodium(III)-catalyzed olefinic C–H alkynylation of enamides at room temperature Chemical Communications. ,vol. 50, pp. 9865- 9868 ,(2014) , 10.1039/C4CC04072D
Ramesh Giri, Bing-Feng Shi, Keary M. Engle, Nathan Maugel, Jin-Quan Yu, Transition metal-catalyzed C–H activation reactions: diastereoselectivity and enantioselectivity Chemical Society Reviews. ,vol. 38, pp. 3242- 3272 ,(2009) , 10.1039/B816707A