Dickdarmmikrobiom und Depression

摘要: Microbiological ecology and its ambition to describe the complete genome of complex living communities as a whole, have given us powerful tools characterize human gut microbiome on genetic and, hence, taxonomic abundance level; for decade now, they become sufficiently inexpensive, fast feasible. Thus, opportunities arose fresh closer look at microbiota-gut-brain-axis impact health; this axis comprises multisystemic network multidirectional interactions between brain including influences beyond one generation. Gnotobiotic animal models essential specific research targets. Combining analysis with observations hypothalamus-pituitary-adrenal various aspects inflammation helped gain first insights into role in depressive disorders. Therapeutic endeavors psychobiotics not yet shown their value clinical studies.