Low rates of adjuvant radiation in patients with nonmetastatic prostate cancer with high‐risk pathologic features

摘要: BACKGROUND The 2013 American Urological Association/American Society for Radiation Oncology consensus guidelines recommend offering adjuvant radiotherapy (RT) after radical prostatectomy in patients with high-risk pathologic features recurrence. In the current study, authors examined practice patterns of RT use elevated risk factors over a time period spanning publication supporting randomized evidence. METHODS Using National Cancer Data Base, total 130,681 were identified who underwent surgical resection prostate cancer between 2004 and 2011 at least 1 following early biochemical failure: pT3a disease or higher, positive margins and/or lymph node-positive disease. Using multivariable logistic regression, associated including patient, clinical, demographic, temporal characteristics. RESULTS Adjuvant was administered to 9.9% factor. Use did not change study (P = .23). On analysis, we found that treated high-volume facilities less likely receive (15.9% vs 7.8%; odds ratio, 0.58 [95% confidence interval, 0.50-0.65]; P < .0001). Older age, comorbidities, black race, lower income, population density also rates RT. CONCLUSIONS Use is uncommon remained unchanged 2011. Patients are RT, irrespective margin status. 2014;120:3089–3096. © 2014 Society.