TRAIL (Apo2 Ligand) and TWEAK (Apo3 Ligand) Mediate CD4+T Cell Killing of Antigen-Presenting Macrophages

作者: Mariana J. Kaplan , Donna Ray , Ru-Ran Mo , Raymond L. Yung , Bruce C. Richardson

DOI: 10.4049/JIMMUNOL.164.6.2897

关键词:

摘要: … also reported that a more promiscuous Mφ killing by autoreactive CD4 T cells may provide a source of antigenic nucleic acids in a lupus model (9, 10) and in patients with active lupus (…

参考文章(46)
R H Schwartz, J D Ashwell, B S Fox, Functional analysis of the interaction of the antigen-specific T cell receptor with its ligands. Journal of Immunology. ,vol. 136, pp. 757- 768 ,(1986)
L L Lanier, J H Phillips, M Cayabyab, CD40 preferentially costimulates activation of CD4+ T lymphocytes. Journal of Immunology. ,vol. 152, pp. 1523- 1531 ,(1994)
William E. Biddison, Henry F. McFarland, Paolo A. Muraro, Apurva Sarin, Bernhard Hemmer, Roland Martin, Laura Tranquill, Marco Vergelli, HUMAN AUTOREACTIVE CD4+ T CELL CLONES USE PERFORIN- OR FAS/FAS LIGAND-MEDIATED PATHWAYS FOR TARGET CELL LYSIS Journal of Immunology. ,vol. 158, pp. 2756- 2761 ,(1997)
Samir M. Hanash, Nahid Hemati, Bruce C. Richardson, Bruce C. Richardson, Jun Yang, Chun Deng, Effect of mitogenic stimulation and DNA methylation on human T cell DNA methyltransferase expression and activity. Journal of Immunology. ,vol. 159, pp. 1303- 1309 ,(1997)
Jawaid Quddus, C. E. Chrisp, R. L. Yung, B. C. Richardson, K. J. Johnson, Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo. Journal of Immunology. ,vol. 154, pp. 3025- 3035 ,(1995)
D F Mangan, B Robertson, S M Wahl, IL-4 enhances programmed cell death (apoptosis) in stimulated human monocytes. Journal of Immunology. ,vol. 148, pp. 1812- 1816 ,(1992)
D. W. Lancki, F. W. Fitch, Chyi-Song Hsieh, Mechanisms of lysis by cytotoxic T lymphocyte clones. Lytic activity and gene expression in cloned antigen-specific CD4+ and CD8+ T lymphocytes. Journal of Immunology. ,vol. 146, pp. 3242- 3249 ,(1991)