Biomarkers Of Chronic Stress

作者: Laalithya Konduru

DOI:

关键词:

摘要: Stress is defined as the internal process that occurs when a person faced with demand perceived to exceed resources available effectively deal it. It can be either acute or chronic. The current approaches measure stress include self reports, measures of affect, stressor exposure and use biomarkers. This paper seeks act review various neuroendocrine biomarkers for chronic stress. A brief overview metabolic immunological also included. Serum cholesterol, serum albumin, waist-hip ratio glycosylated hemoglobin are some common IL-6, TNF-α, CRP IGF-1 Neuroendocrine factors effective because they first respond given coordinate response many other biological systems. Cortisol, DHEA, adrenaline, noradrenaline, dopamine aldosterone commonly used Use any single biomarker associated problems multiple determination. Allostatic load model utilizes suite indicators effects across physiological novel technologies like metabolomics, determining changes in ultrastructure mitochondria quantifying induction DRR1 brain interesting research areas could throw up Chronic diseases. possibly potentiate health exposures thus, it an important public concern. In order conduct on condition, characterize condition. Biomarkers help objectively. Stress, unlike pathological triggers non-specific influences Ideally, study would set response, while using questionnaires appraisal. challenge lies coming capture related information weed out confounding factors.

参考文章(176)
C A Dinarello, Interleukin-1 and tumor necrosis factor: effector cytokines in autoimmune diseases. Seminars in Immunology. ,vol. 4, pp. 133- 145 ,(1992)
Peter Sterling, Joseph Eyer, Allostasis: A new paradigm to explain arousal pathology. Handbook of Life Stress, Cognition and Health. ,(1988)
Thomas List, Kerstin Wahlund, Bo Larsson, Psychosocial functioning and dental factors in adolescents with temporomandibular disorders: a case-control study. Journal of Orofacial Pain. ,vol. 15, pp. 218- 227 ,(2001)
Takeyasu M, Kato T, Urinary excretion of dehydroepiandrosterone and its metabolites in normal young adult women The Japanese journal of clinical pathology. ,vol. 46, pp. 1241- ,(1998)
Marianne Frankenhaeuser, A Psychobiological Framework for Research on Human Stress and Coping Springer, Boston, MA. pp. 101- 116 ,(1986) , 10.1007/978-1-4684-5122-1_6
Uday S. Nori, Anup Manoharan, John I. Thornby, Jerry Yee, Ravi Parasuraman, Venkataraman Ramanathan, Mortality risk factors in chronic haemodialysis patients with infective endocarditis Nephrology Dialysis Transplantation. ,vol. 21, pp. 2184- 2190 ,(2006) , 10.1093/NDT/GFL200
Eileen M. Crimmins, Melanie Johnston, Mark Hayward, Teresa Seeman, Age differences in allostatic load: an index of physiological dysregulation Experimental Gerontology. ,vol. 38, pp. 731- 734 ,(2003) , 10.1016/S0531-5565(03)00099-8
Yong-Jin Chen, Fei Huang, Min Zhang, Hai-Yan Shang, Psychological Stress Alters Ultrastructure and Energy Metabolism of Masticatory Muscle in Rats BioMed Research International. ,vol. 2010, pp. 302693- 302693 ,(2010) , 10.1155/2010/302693
Bruce S. McEwen, Peter J. Gianaros, Stress- and Allostasis-Induced Brain Plasticity Annual Review of Medicine. ,vol. 62, pp. 431- 445 ,(2011) , 10.1146/ANNUREV-MED-052209-100430