Reflex regulation of autonomic influences upon the oxytocin-induced contractile response of the mammary gland in the anesthetized rat.

摘要: Intramammary pressure (IMP) from an abdominal mammary gland, generated in response to intrajugular injections of oxytocin, were recorded before, during, and after 120–140 sec electrical stimulation the cut central end a contralateral nerve urethane-anesthetized lactating rat. The parameters 5- 30-V 1-msec pulses at frequency 10/sec. amplitude IMP responses given dose oxytocin was reduced by about 50% when tested 60 120 recovered prestimulus heights 3–10 min cessation stimulus. depressant effect then could be repeated. Bilateral adrenal ligature, iv injection 0.3 mg propranolol, or section spinal cord above level entry completely blocked stimulation. In fact, slope eventually increased that found before each th...