Comprehensive assessment of cancer missense mutation clustering in protein structures
作者： Atanas Kamburov , Michael S. Lawrence , Paz Polak , Ignaty Leshchiner , Kasper Lage
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摘要: Large-scale tumor sequencing projects enabled the identification of many new cancer gene candidates through computational approaches. Here, we describe a general method to …
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Nina Korzeniewski, Markus Hohenfellner, Stefan Duensing, CAND1 promotes PLK4-mediated centriole overduplication and is frequently disrupted in prostate cancer. Neoplasia. ,vol. 14, pp. 799- 806 ,(2012) , 10.1593/NEO.12580
Gerrit M Daubner, Antoine Cléry, Sandrine Jayne, James Stevenin, Frédéric H-T Allain, A syn–anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well The EMBO Journal. ,vol. 31, pp. 162- 174 ,(2012) , 10.1038/EMBOJ.2011.367
Jie-Oh Lee, Haijuan Yang, Maria-Magdalena Georgescu, Antonio Di Cristofano, Tomohiko Maehama, Yigong Shi, Jack E Dixon, Pier Pandolfi, Nikola P Pavletich, Crystal Structure of the PTEN Tumor Suppressor: Implications for Its Phosphoinositide Phosphatase Activity and Membrane Association Cell. ,vol. 99, pp. 323- 334 ,(1999) , 10.1016/S0092-8674(00)81663-3
Igor Vivanco, H. Ian Robins, Daniel Rohle, Carl Campos, Christian Grommes, Phioanh Leia Nghiemphu, Sara Kubek, Barbara Oldrini, Milan G. Chheda, Nicolas Yannuzzi, Hui Tao, Shaojun Zhu, Akio Iwanami, Daisuke Kuga, Julie Dang, Alicia Pedraza, Cameron W. Brennan, Adriana Heguy, Linda M. Liau, Frank Lieberman, W. K. Alfred Yung, Mark R. Gilbert, David A. Reardon, Jan Drappatz, Patrick Y. Wen, Kathleen R. Lamborn, Susan M. Chang, Michael D. Prados, Howard A. Fine, Steve Horvath, Nian Wu, Andrew B. Lassman, Lisa M. DeAngelis, William H. Yong, John G. Kuhn, Paul S. Mischel, Minesh P. Mehta, Timothy F. Cloughesy, Ingo K. Mellinghoff, Differential Sensitivity of Glioma- versus Lung Cancer–Specific EGFR Mutations to EGFR Kinase Inhibitors Cancer Discovery. ,vol. 2, pp. 458- 471 ,(2012) , 10.1158/2159-8290.CD-11-0284
C.-H. Huang, D. Mandelker, O. Schmidt-Kittler, Y. Samuels, V. E. Velculescu, K. W. Kinzler, B. Vogelstein, S. B. Gabelli, L. M. Amzel, The Structure of a Human p110α/p85α Complex Elucidates the Effects of Oncogenic PI3Kα Mutations Science. ,vol. 318, pp. 1744- 1748 ,(2007) , 10.1126/SCIENCE.1150799
Papia Ghosh, Min Wu, Hui Zhang, Hong Sun, mTORC1 signaling requires proteasomal function and the involvement of CUL4-DDB1 ubiquitin E3 ligase Cell Cycle. ,vol. 7, pp. 373- 381 ,(2008) , 10.4161/CC.7.3.5267
Peng Hu, Xi Chen, Jing Sun, Ping Bie, Lei-Da Zhang, siRNA-mediated knockdown against NUF2 suppresses pancreatic cancer proliferation in vitro and in vivo. Bioscience Reports. ,vol. 35, pp. 1- 11 ,(2015) , 10.1042/BSR20140124
Satoshi Hayama, Yataro Daigo, Tatsuya Kato, Nobuhisa Ishikawa, Takumi Yamabuki, Masaki Miyamoto, Tomoo Ito, Eiju Tsuchiya, Satoshi Kondo, Yusuke Nakamura, Activation of CDCA1-KNTC2, Members of Centromere Protein Complex, Involved in Pulmonary Carcinogenesis Cancer Research. ,vol. 66, pp. 10339- 10348 ,(2006) , 10.1158/0008-5472.CAN-06-2137
Anna A. Sablina, Wen Chen, Jason D. Arroyo, Laura Corral, Melissa Hector, Sara E. Bulmer, James A. DeCaprio, William C. Hahn, The Tumor Suppressor PP2A Aβ Regulates the RalA GTPase Cell. ,vol. 129, pp. 969- 982 ,(2007) , 10.1016/J.CELL.2007.03.047
Bing Hao, Stephanie Oehlmann, Mathew E. Sowa, J. Wade Harper, Nikola P. Pavletich, Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases. Molecular Cell. ,vol. 26, pp. 131- 143 ,(2007) , 10.1016/J.MOLCEL.2007.02.022