Aggression in non-human vertebrates: Genetic mechanisms and molecular pathways

作者: Florian Freudenberg , Hector Carreño Gutierrez , Antonia M. Post , Andreas Reif , William H. J. Norton

DOI: 10.1002/AJMG.B.32358

关键词:

摘要: Aggression is an adaptive behavioral trait that important for the establishment of social hierarchies and competition mating partners, food, territories. While a certain level aggression can be beneficial survival individual or species, abnormal levels detrimental. Abnormal commonly found in human patients with psychiatric disorders. The predisposition to influenced by combination environmental genetic factors large number genes have been associated both animal studies. In this review, we compare contrast studies zebrafish mouse. We present gene ontology pathway analyses linked discuss molecular pathways underpin agonistic behavior these species. © 2015 Wiley Periodicals, Inc.

参考文章(294)
Brian C. Trainor, Kelly M. Greiwe, Randy J. Nelson, Individual differences in estrogen receptor α in select brain nuclei are associated with individual differences in aggression Hormones and Behavior. ,vol. 50, pp. 338- 345 ,(2006) , 10.1016/J.YHBEH.2006.04.002
T. Karl, S. Lin, C. Schwarzer, A. Sainsbury, M. Couzens, W. Wittmann, D. Boey, S. von Horsten, H. Herzog, Y1 receptors regulate aggressive behavior by modulating serotonin pathways Proceedings of the National Academy of Sciences of the United States of America. ,vol. 101, pp. 12742- 12747 ,(2004) , 10.1073/PNAS.0404085101
Siobhan Robinson, Carlos A.A. Penatti, Ann S. Clark, The role of the androgen receptor in anabolic androgenic steroid-induced aggressive behavior in C57BL/6J and Tfm mice. Hormones and Behavior. ,vol. 61, pp. 67- 75 ,(2012) , 10.1016/J.YHBEH.2011.10.004
Ankur Patel, Allan Siegel, Steven S. Zalcman, Lack of aggression and anxiolytic-like behavior in TNF receptor (TNF-R1 and TNF-R2) deficient mice. Brain Behavior and Immunity. ,vol. 24, pp. 1276- 1280 ,(2010) , 10.1016/J.BBI.2010.05.005
Allan V. Kalueff, Adam Michael Stewart, Robert Gerlai, Zebrafish as an emerging model for studying complex brain disorders. Trends in Pharmacological Sciences. ,vol. 35, pp. 63- 75 ,(2014) , 10.1016/J.TIPS.2013.12.002
Takahiro Matsumoto, Shin-ichiro Honda, Nobuhiro Harada, Alteration in Sex-Specific Behaviors in Male Mice Lacking the Aromatase Gene Neuroendocrinology. ,vol. 77, pp. 416- 424 ,(2003) , 10.1159/000071313
Martin E. Hahn, Norman Schanz, Issues in the genetics of social behavior: revisited. Behavior Genetics. ,vol. 26, pp. 463- 470 ,(1996) , 10.1007/BF02359750
Masayoshi Nomura, Larissa Durbak, Johnny Chan, Oliver Smithies, Jan-Åke Gustafsson, Kenneth S. Korach, Donald W. Pfaff, Sonoko Ogawa, Genotype/Age Interactions on Aggressive Behavior in Gonadally Intact Estrogen Receptor β Knockout (βERKO) Male Mice Hormones and Behavior. ,vol. 41, pp. 288- 296 ,(2002) , 10.1006/HBEH.2002.1773
Johannes Breu, Chadi Touma, Sabine M. Hölter, Alana Knapman, Wolfgang Wurst, Jan M. Deussing, Urocortin 2 modulates aspects of social behaviour in mice. Behavioural Brain Research. ,vol. 233, pp. 331- 336 ,(2012) , 10.1016/J.BBR.2012.05.031
Alaine C. Keebaugh, Heather A. Mitchell, Meriem Gaval-Cruz, Kimberly G. Freeman, Gaylen L. Edwards, David Weinshenker, James W. Thomas, PRTFDC1 Is a Genetic Modifier of HPRT-Deficiency in the Mouse PLoS ONE. ,vol. 6, pp. e22381- ,(2011) , 10.1371/JOURNAL.PONE.0022381