Viral infections and their impact on chronic renal allograft dysfunction.

摘要: Viral infections, particularly those involving HCMV, are an important complication of renal transplantation. Transplantation protocols and treatment regimens that increase HCMV infection disease may promote the development CRAD impair long-term allograft survival. Investigators beginning to illuminate mechanisms by which cause chronic rejection in general transplant vascular sclerosis particular. Migration proliferation SMCs within intimal layer blood vessels is component sclerosis, appears facilitate both these processes. Current management strategies for focus on prevention, either using a focal preemptive therapeutic approach or administering antiviral therapies all at-risk patients.