Expression of connexin31 and connexin43 genes in early rat embryos
作者： B. Reuss , P. Hellmann , O. Traub , A. Butterweck , E. Winterhager
DOI: 10.1002/(SICI)1520-6408(1997)21:1<82::AID-DVG10>3.0.CO;2-C
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摘要: Gap junctions have been reported to play a pivotal role in coordinating embryonic development. Here we report the temporal and spatial pattern of connexin31 that has found be coexpressed with connexin43 preimplantation rat embryos. Connexin31 transcripts are abundant zygote degraded two- four-cell stage low levels for undetectable ones connexin43. The uncompacted eight-cell lacks both connexins. Reexpression mRNA is from compacted onward. antigen, however, already detected intracellularly at stage. At blastocyst stage, connexins trophectoderm as well inner cell mass. After implantation, compartmentalization observed. now expressed exclusively by cells ectoplacental cone extraembryonic ectoderm, whereas restricted embryo proper. This connexin expression between derivatives mass may maintain different developmental programs. THus, seems not related first step trophoblast lineage development could serve compensatory channel during
sci-hub.se 参考文章(41)
Michael N. Waltzman, David C. Spray, Exogenous Expression of Connexins for Physiological Characterization of Channel Properties: Comparison of Methods and Results Intercellular Communication through Gap Junctions. ,vol. 4, pp. 9- 17 ,(1995) , 10.1016/B978-0-444-81929-1.50005-8
Brigid Hogan, Elizabeth Lacy, Frank Costantini, Manipulating the mouse embryo: A laboratory manual ,(1986)
F. Allen, A. Warner, C. Tickle, The role of gap junctions in patterning of the chick limb bud Development. ,vol. 108, pp. 623- 634 ,(1990)
Tzu-Ping Lin, Patricia A. Labosky, Laura B. Grabel, Christine A. Kozak, Jeffrey L. Pitman, Jeanine Kleeman, Carol L. MacLeod, The Pem homeobox gene is X-linked and exclusively expressed in extraembryonic tissues during early murine development. Developmental Biology. ,vol. 166, pp. 170- 179 ,(1994) , 10.1006/DBIO.1994.1305
Gunnar Valdimarsson, Paul A. De Sousa, Eric C. Beyer, David L. Paul, Gerald M. Kidder, Zygotic expression of the connexin43 gene supplies subunits for gap junction assembly during mouse preimplantation development. Molecular Reproduction and Development. ,vol. 30, pp. 18- 26 ,(1991) , 10.1002/MRD.1080300103
Cecilia W. Lo, Norton B. Gilula, Gap junctional communication in the post-implantation mouse embryo Cell. ,vol. 18, pp. 411- 422 ,(1979) , 10.1016/0092-8674(79)90060-6
Tyler C. Davies, Kevin J. Barr, D. Holstead Jones, Daguang Zhu, Gerald M. Kidder, Multiple members of the connexin gene family participate in preimplantation development of the mouse Developmental Genetics. ,vol. 18, pp. 234- 243 ,(1996) , 10.1002/(SICI)1520-6408(1996)18:3<234::AID-DVG4>3.0.CO;2-A
Ghulam H Kalimi, Cecilia W Lo, Gap junctional communication in the extraembryonic tissues of the gastrulating mouse embryo. Journal of Cell Biology. ,vol. 109, pp. 3015- 3026 ,(1989) , 10.1083/JCB.109.6.3015
Dietmar Vestweber, Achim Gossler, Klaus Boller, Rolf Kemler, Expression and distribution of cell adhesion molecule uvomorulin in mouse preimplantation embryos Developmental Biology. ,vol. 124, pp. 451- 456 ,(1987) , 10.1016/0012-1606(87)90498-2
Jeanne R. McLachlin, Stanley Caveney, Gerald M. Kidder, Control of gap junction formation in early mouse embryos Developmental Biology. ,vol. 98, pp. 155- 164 ,(1983) , 10.1016/0012-1606(83)90344-5