Spectroscopic, structural characterizations and antioxidant capacity of the chromium (III) niacinamide compound as a diabetes mellitus drug model.
作者： Moamen S. Refat , Samy M. El-Megharbel , M.A. Hussien , Reham Z. Hamza , Mohamed A. Al-Omar
DOI: 10.1016/J.SAA.2016.08.053
关键词:
摘要: New binuclear chromium (III) niacinamide compound with chemical formula [Cr2(Nic)(Cl)6(H2O)4]·H2O was obtained upon the reaction of chloride (Nic) in methanol solvent at 60°C. The proposed structure discussed help microanalytical analyses, conductivity, spectroscopic (FT-IR and UV-vis.), magnetic calculations, thermogravimetric analyses (TG/TGA), morphological studies (X-ray solid powder scan electron microscopy. infrared spectrum free comparison its indicated that chelation mode occurs via both nitrogen atoms pyridine ring primary -NH2 group. efficiency decreasing glucose level blood HbA1c case diabetic rats checked. ameliorating gluconeogenic enzymes, lipid profile antioxidant defense capacities are considered as an indicator new antidiabetic drug model.
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