The early effects of ischemia upon skeletal muscle mitochondria

摘要: Abstract The effects of early ischemia were studied in the anterior tibial muscle Sprague-Dawley rats after 2–24 hr tourniquet compression at thigh. Ragged-red fibers, moth-eaten cores and targets seen tissue examined by enzyme histochemistry electron microscopy. Giant mitochondria, abnormalities cristal arrangement, crystalloids, osmiophilic inclusion bodies myeloid figures dominant features mitochondrial reaction. results this experiment indicate that induces a variety changes described other neuromuscular conditions such as dystrophy “mitochondrial myopathies.” pathogenesis these their relationship to human disease is discussed.