Meta-analysis of Soy Consumption and Gastrointestinal Cancer Risk.

作者: Demin Lu , Chi Pan , Chenyang Ye , Huijie Duan , Fei Xu

DOI: 10.1038/S41598-017-03692-Y

关键词:

摘要: Soy consumption has received considerable attention for its potential role in reducing cancer incidence and mortality. However, effects on gastrointestinal (GI) are controversial. Therefore, we performed a meta-analysis to evaluate the association between soy risk by searching prospective studies PubMed, Web of Science, EMBASE reference lists included articles. The study-specific odds ratio (OR), relative (RR) or hazard (HR) estimates 95% confidence intervals (CIs) were pooled using either fixed-effect random-effect model. Twenty-two independent eligible our meta-analysis, including 21 cohort one nested case-control study. product was inversely associated with overall GI (0.857; CI: 0.766, 0.959) gastric subgroup (0.847; 0.722, 0.994) but not colorectal subgroup. After stratifying results according gender, an inverse observed intake females (0.711; 0.506, 0.999) males.

参考文章(73)
Hiroyasu Iso, Yoshimi Kubota, Nutrition and disease in the Japan Collaborative Cohort Study for Evaluation of Cancer (JACC). Asian Pacific Journal of Cancer Prevention. pp. 35- 80 ,(2007)
Fazlul H. Sarkar, Yiwei Li, Mechanisms of cancer chemoprevention by soy isoflavone genistein. Cancer and Metastasis Reviews. ,vol. 21, pp. 265- 280 ,(2002) , 10.1023/A:1021210910821
Lucy Sayuri Ito, Manami Inoue, Kazuo Tajima, Yoshitaka Yamamura, Yasuhiro Kodera, Kaoru Hirose, Toshiro Takezaki, Nobuyuki Hamajima, Tetsuo Kuroishi, Suketami Tominaga, Dietary Factors and the Risk of Gastric Cancer Among Japanese Women: a Comparison Between the Differentiated and Non-Differentiated Subtypes Annals of Epidemiology. ,vol. 13, pp. 24- 31 ,(2003) , 10.1016/S1047-2797(02)00269-7
W C Willett, G R Howe, L H Kushi, Adjustment for total energy intake in epidemiologic studies The American Journal of Clinical Nutrition. ,vol. 65, ,(1997) , 10.1093/AJCN/65.4.1220S
Mitsumasa Umesawa, Hiroyasu Iso, Yoshihisa Fujino, Shogo Kikuchi, Akiko Tamakoshi, Salty Food Preference and Intake and Risk of Gastric Cancer : The JACC Study Journal of Epidemiology. ,vol. 26, pp. 92- 97 ,(2016) , 10.2188/JEA.JE20150023
SANDER GREENLAND, QUANTITATIVE METHODS IN THE REVIEW OF EPIDEMIOLOGIC LITERATURE Epidemiologic Reviews. ,vol. 9, pp. 1- 30 ,(1987) , 10.1093/OXFORDJOURNALS.EPIREV.A036298
Grant N. Stemmermann, Abraham Nomura, Richard K. Severson, John S. Grove, A Prospective Study of Stomach Cancer and Its Relation to Diet, Cigarettes, and Alcohol Consumption Cancer Research. ,vol. 50, pp. 627- 631 ,(1990)
Heiying Jin, Qiang Leng, Chunbo Li, Dietary flavonoid for preventing colorectal neoplasms Cochrane Database of Systematic Reviews. ,vol. 8, ,(2012) , 10.1002/14651858.CD009350.PUB2
Colin B. Begg, Madhuchhanda Mazumdar, Operating characteristics of a rank correlation test for publication bias. Biometrics. ,vol. 50, pp. 1088- 1101 ,(1994) , 10.2307/2533446