Systemic immunity in herpetic keratitis.

摘要: The importance of specific immunity, especially cell-mediated, in resistance to herpes simplex disease is well documented, and animal experiments show that immune responses previous herpetic infection can give considerable protection against reinfection epithelial keratitis. Since susceptibility stromal keratitis probably determined part by the extent virus proliferation epithelium, were studied patients with or keratitis, a group who also severely atopic, controls. parameters measured lymphocyte transformation, production macrophage migration inhibition factor, levels serum antibody immunoglobulin. No differences found except for slight decrease whole blood culture assessment transformation compared seropositive controls disease. It considered small deficiency cell-mediated response plays role determining spread into corneal stroma.