Altered permeability in inflammatory bowel disease: pathophysiology and clinical implications.

作者: Joachim Mankertz , J??rg-Dieter Schulzke

DOI: 10.1097/MOG.0B013E32816AA392

关键词:

摘要: … Barrier dysfunction in inflammatory bowel disease … and are the result of immune dysregulation. Studying the underlying … pathophysiology of inflammatory bowel disease and developing …

参考文章(61)
Shoichiro Tsukita, Mikio Furuse, Masahiko Itoh, Multifunctional strands in tight junctions. Nature Reviews Molecular Cell Biology. ,vol. 2, pp. 285- 293 ,(2001) , 10.1038/35067088
Henry J. Leese, M. Reza Ghassemifar, Franchesca D. Houghton, Tom P. Fleming, Bhavwanti Sheth, Tom Papenbrock, Occludin TM4(-): an isoform of the tight junction protein present in primates lacking the fourth transmembrane domain. Journal of Cell Science. ,vol. 115, pp. 3171- 3180 ,(2002) , 10.1242/JCS.115.15.3171
Salah Amasheh, Thomas Schmidt, Michaela Mahn, Peter Florian, Joachim Mankertz, Shida Tavalali, Alfred H. Gitter, Jörg-Dieter Schulzke, Michael Fromm, Contribution of claudin-5 to barrier properties in tight junctions of epithelial cells. Cell and Tissue Research. ,vol. 321, pp. 89- 96 ,(2005) , 10.1007/S00441-005-1101-0
Daniel Hollander, Crohn's disease, TNF-α, and the leaky gut. the chicken or the egg? The American Journal of Gastroenterology. ,vol. 97, pp. 1867- 1868 ,(2002) , 10.1111/J.1572-0241.2002.05895.X
Peter Suenaert, Veerle Bulteel, Severine Vermeire, Maja Noman, Gert Van Assche, Paul Rutgeerts, Hyperresponsiveness of the mucosal barrier in Crohn's disease is not tumor necrosis factor-dependent. Inflammatory Bowel Diseases. ,vol. 11, pp. 667- 673 ,(2005) , 10.1097/01.MIB.0000168371.87283.4B
Mike G Laukoetter, Matthias Bruewer, Asma Nusrat, Regulation of the intestinal epithelial barrier by the apical junctional complex. Current Opinion in Gastroenterology. ,vol. 22, pp. 85- 89 ,(2006) , 10.1097/01.MOG.0000203864.48255.4F
Janiel M. Shields, Robert J. Christy, Vincent W. Yang, Identification and Characterization of a Gene Encoding a Gut-enriched Krüppel-like Factor Expressed during Growth Arrest Journal of Biological Chemistry. ,vol. 271, pp. 20009- 20017 ,(1996) , 10.1074/JBC.271.33.20009
J.-D. SCHULZKE, C. BOJARSKI, S. ZEISSIG, F. HELLER, A. H GITTER, M. FROMM, Disrupted Barrier Function through Epithelial Cell Apoptosis Annals of the New York Academy of Sciences. ,vol. 1072, pp. 288- 299 ,(2006) , 10.1196/ANNALS.1326.027
T. T. MACDONALD, P. HUTCHINGS, M.-Y. CHOY, S. MURCH, A. COOKE, Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine. Clinical and Experimental Immunology. ,vol. 81, pp. 301- 305 ,(2008) , 10.1111/J.1365-2249.1990.TB03334.X