Biological behavior of mesenchymal stem cells on poly-ε-caprolactone filaments and a strategy for tissue engineering of segments of the peripheral nerves

作者: A. Carrier-Ruiz , F. Evaristo-Mendonça , R. Mendez-Otero , V. T. Ribeiro-Resende

DOI: 10.1186/S13287-015-0121-2

关键词:

摘要: Introduction Peripheral nerves may fail to regenerate across tube implants because these lack the microarchitecture of native nerves. Bone marrow mesenchymal stem cells (MSC) secrete soluble factors that improve regeneration peripheral Also, microstructured poly-caprolactone (PCL) filaments are capable inducing bands Bungner and promote in nervous system (PNS). We describe here interaction between PCL MSC, aiming optimize PNS tubular implants.

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