Aging changes in the human brain: A histochemical and immunohistochemical study

作者: Sambit K Mohanty , Bishan D Radotra , Ashru K Banerjee

DOI: 10.1111/J.1440-1789.2003.00498.X

关键词:

摘要: There are very few studies on neuropathological changes of aging in the Indian population. In present study, incidence 20 non-demented elderly humans above age 55 years were observed. The neurofibrillary tangles (NFT) increased from 20% 50-55-year-olds to 80% 55-year-olds and over. Senile plaques (SP) 55-60-year-olds 40% 60-year-olds results immunohistochemistry label NFT (Tau) SP (beta-amyloid) comparable Bielchowsky's modified silver methanamine method. related their antigenic character limited sample studied north-west India appear be those southern part Western hemisphere.

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