作者: Elizabeth M. Blanchard , Konstantinos Arnaoutakis , Paul J. Hesketh
DOI: 10.1097/JTO.0B013E3181D89B48
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摘要: Background Lung cancer has progressively become a disease of older people, with the median age at diagnosis now exceeding 70 years. Octogenarians represent rapidly growing proportion patients diagnosed lung and can present distinct challenges. Nevertheless, current literature that set evidence-based standards care in this does not include significant numbers than 80 Methods We have compiled reviewed available on specific management treatment Results Retrospective series suggest surgery is safe effective treating early-stage non-small cell selected There minimal data to support use adjuvant chemotherapy group. In addition, no exist combined radiotherapy for locally advanced disease. or metastatic disease, similar younger elderly populations, single-agent feasible seems offer benefit terms symptoms outcomes. Small population well characterized, but small studies symptom improvement prolongation survival chemotherapy. Conclusion Based retrospective series, octogenarians derive from many modalities used including More trials are needed better refine decisions improve