Detection of genome editing
作者： Jennifer Berman , Bruce Conklin , Yuichiro Miyaoka , George Karlin-Neumann , Samantha Cooper
DOI:
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摘要: Methods, compositions, and kits are provided for quantification of genome editing. In one aspect, the present invention provides a method simultaneous homology directed repair (HDR) non-homologous end joining (NHEJ) editing products in sample cells, wherein said cells has been contacted with site-specific reagent configured to cleave or nick DNA target enomic region an HDR template nucleic acid.
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