Role of stearoyl-CoA desaturase in human metabolic disease

作者: Harini Sampath , James M Ntambi

DOI: 10.2217/17460875.3.2.163

关键词:

摘要: … It is increasingly evident that derangements in lipid metabolism play a significant role in the development of the metabolic syndrome. Increased circulating lipids, either from the diet or …

参考文章(94)
Monika Eichholzer, Holger Moch, Michela Ceschi, Nicole M Probst-Hensch, Felix Gutzwiller, Epidemiology and pathophysiology of obesity as cause of cancer. Swiss Medical Weekly. ,vol. 137, pp. 50- 56 ,(2007) , 10.5167/UZH-17805
K. Schoonjans, J. Peinado-Onsurbe, A. M. Lefebvre, R. A. Heyman, M. Briggs, S. Deeb, B. Staels, J. Auwerx, PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene The EMBO Journal. ,vol. 15, pp. 5336- 5348 ,(1996) , 10.1002/J.1460-2075.1996.TB00918.X
Bret H Goodpaster, F Leland Thaete, David E Kelley, Thigh adipose tissue distribution is associated with insulin resistance in obesity and in type 2 diabetes mellitus. The American Journal of Clinical Nutrition. ,vol. 71, pp. 885- 892 ,(2000) , 10.1093/AJCN/71.4.885
François Paillard, Daniel Catheline, Franck Le Duff, Monique Bouriel, Yves Deugnier, Michel Pouchard, Jean-Claude Daubert, Philippe Legrand, Plasma palmitoleic acid, a product of stearoyl-coA desaturase activity, is an independent marker of triglyceridemia and abdominal adiposity Nutrition Metabolism and Cardiovascular Diseases. ,vol. 18, pp. 436- 440 ,(2008) , 10.1016/J.NUMECD.2007.02.017
Makoto Miyazaki, Young-Cheul Kim, Mark P. Gray-Keller, Alan D. Attie, James M. Ntambi, The Biosynthesis of Hepatic Cholesterol Esters and Triglycerides Is Impaired in Mice with a Disruption of the Gene for Stearoyl-CoA Desaturase 1 Journal of Biological Chemistry. ,vol. 275, pp. 30132- 30138 ,(2000) , 10.1074/JBC.M005488200
Bo Isomaa, A major health hazard: the metabolic syndrome. Life Sciences. ,vol. 73, pp. 2395- 2411 ,(2003) , 10.1016/S0024-3205(03)00646-5
Alpa V Patel, Carmen Rodriguez, Leslie Bernstein, Ann Chao, Michael J Thun, Eugenia E Calle, Obesity, Recreational Physical Activity, and Risk of Pancreatic Cancer In a Large U.S. Cohort Cancer Epidemiology Biomarkers & Prevention. ,vol. 14, pp. 459- 466 ,(2005) , 10.1158/1055-9965.EPI-04-0583
Srinivas B. Narayan, Dinesh Rakheja, Lu Tan, Johanne V. Pastor, Michael J. Bennett, CLN3P, the Batten's disease protein, is a novel palmitoyl-protein Δ-9 desaturase Annals of Neurology. ,vol. 60, pp. 570- 577 ,(2006) , 10.1002/ANA.20975