Longitudinal association between depressive symptoms and walking impairment in people with relapsing-remitting multiple sclerosis

作者: Ipek Ensari , Brynn C Adamson , Robert W Motl

DOI: 10.1177/1359105315584837

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摘要: Worsening depressive symptoms and walking impairment are significant burdens in multiple sclerosis. We explored the reciprocal relationship between a cohort of 269 people with relapsing-remitting sclerosis over 2 years. The data were examined using longitudinal panel analysis Mplus. Baseline predicted change at 1-year follow-up (path coefficient = .074), 2-year coefficient = .177). Our study provides preliminary evidence for initiation

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