作者: L. Benjamin , F.-E. Cotté , F. Mercier , A. Vainchtock , G. Vidal-Trécan
DOI: 10.3111/13696998.2012.662924
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摘要: AbstractObjective:Incidence of breast cancer with brain metastases (BCBM) is increasing, especially among patients over-expressing HER2. Epidemiology on this sub-type scarce, since registries carry no information the HER2 status. A retrospective database analysis was conducted to estimate burden BCBM, HER2-positive in a secondary objective.Methods:Patients new diagnosis BCBM carried out between January and December 2008 were identified from national hospital using International Disease Classification. Patients receiving targeted anti-HER2 therapy pharmacy database. Hospital claims linked patients. Data hospitalizations extracted describe treatment patterns healthcare costs during 1-year follow-up. Predictors cost analyzed through multi-linear regression analysis.Results:Two thousand ninety-nin...