Creatinine and glomerular filtration rate: evolution of an accommodation

摘要: This brief review examines the history of use creatinine as a measure renal function. While there are more accurate markers glomerular filtration, was chosen for convenience. Since relationship to filtration depends upon tenuous balance counterbalancing factors, practitioners should be alert situations that alter balance. averaging variations over time helps avoid some problems with diurnal in past, present-day reliance equations based solitary serum value is likely amplify those clinical when effect disease, medications, diet and day not considered.