Zymogen/enzyme discrimination using peptide chloromethyl ketones

作者: E B Williams , S Krishnaswamy , K G Mann

DOI: 10.1016/S0021-9258(18)83268-9

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摘要: … The observed reactivity with avidin was used in enzyme “… enzyme present in enzymezymogen mixtures. These reagents … We thus conclude that factor VI1 is a true zymogen, inert in the …

参考文章(41)
Yale Nemerson, Tissue Factor and the Initiation of Blood Coagulation Advances in Experimental Medicine and Biology. ,vol. 214, pp. 83- 94 ,(1987) , 10.1007/978-1-4757-5985-3_7
ED Sprengers, C Kluft, Plasminogen activator inhibitors. Blood. ,vol. 69, pp. 381- 387 ,(1987) , 10.1182/BLOOD.V69.2.381.BLOODJOURNAL692381
Jolyon Jesty, Yale Nemerson, The activation of bovine coagulation factor X. Methods in Enzymology. ,vol. 45, pp. 95- 107 ,(1976) , 10.1016/S0076-6879(76)45014-0
Charles Kettner, Elliott Shaw, [63] Inactivation of trypsin-like enzymes with peptides of arginine chloromethyl ketone Methods in Enzymology. ,vol. 80, pp. 826- 842 ,(1981) , 10.1016/S0076-6879(81)80065-1
M.E. Nesheim, C. Kettner, E. Shaw, K.G. Mann, Cofactor dependence of factor Xa incorporation into the prothrombinase complex. Journal of Biological Chemistry. ,vol. 256, pp. 6537- 6540 ,(1981) , 10.1016/S0021-9258(19)69021-6
S Krishnaswamy, K C Jones, K G Mann, Prothrombinase complex assembly. Kinetic mechanism of enzyme assembly on phospholipid vesicles. Journal of Biological Chemistry. ,vol. 263, pp. 3823- 3834 ,(1988) , 10.1016/S0021-9258(18)68999-9
P.B. Sigler, D.M. Blow, B.W. Matthews, R. Henderson, Structure of Crystalline α-Chymotrypsin II. A Preliminary Report Including a Hypothesis for the Activation Mechanism Journal of Molecular Biology. ,vol. 35, pp. 143- 164 ,(1968) , 10.1016/S0022-2836(68)80043-9