Análisis clínico-epidemiológico de las subfracciones HDL2 y HDL3 en adultos de la ciudad de Maracaibo, Venezuela

摘要: Objective: To carry out a clinical-epidemiological analysis of high-density lipoprotein cholesterol subfractions (HDL-C) in adults from Maracaibo, Venezuela. Materials and methods: A descriptive cross-sectional study the database Metbolic Syndrome Prevalence Maracaibo Study was carried out. HDL3 and HDL2 serum concentration, as well HDL2/HDL3 ratio, were determined 359 individuals of both sexes, over 18 years age. Values obtained evaluated according to sociodemographic, clinical and biochemical characteristics. Results: Mean population age 39.4 ± 15.2 years, 51.5% female. Differences in HDL-C subfraction levels only observed those subjects with low levels. Women with hypertriglyceridemia showed significantly lower HDL3 concentrations than with normal triglycerides (p=0.033), level / ratio higher levels ultra-sensitive C-reactive protein (us-CRP) (p<0.001). concentration HDL2 was men some degree hypertension (p=0.031), insulin resistance (p=0.050) metabolic syndrome (p=0.003); while elevated us-CRP (p=0.011).  Conclusion: show varying behavior Maracaibo. Lower are men, differences HDL-C; no predominance of any subclass biochemical