CHEMICAL CHARACTERIZATION OF NEW ANTIBIOTICS, CEREXINS A AND B

作者: Hiroshi Hinoo , Jun'ichi Shoji

DOI: 10.7164/ANTIBIOTICS.28.60

关键词:

摘要: Acid hydrolysis revealed that the antibiotic cerexin A is constructed with aspartic acid (3), threonine (1), serine valine (2), allo-isoleucine gamma-hydroxylysine tryptophan and a variety of fatty residues. The essential difference between cerexins B concluded to be replacement one residue in by glycine phenylalanine B. Isolation new amino L-threo-gamma-hydroxylysine also described.

参考文章(4)
N. Izumiya, Y. Fujita, F. Irreverre, B. Witkop, The Synthesis of erythro-γ-Hydroxy-L-lysine and Its Nonoccurrence in Collagen* Biochemistry. ,vol. 4, pp. 2501- 2507 ,(1965) , 10.1021/BI00887A033
E. A. BELL, A New Amino-acid, γ-Hydroxyhomoarginine, in Lathyrus Nature. ,vol. 199, pp. 70- 71 ,(1963) , 10.1038/199070A0
JUN''ICHI SHOJI, HIROSHI HINOO, YOSHIHARU WAKISAKA, KENZO KOIZUMI, MIKAO MAYAMA, SHINZO MATSUURA, KOICHI MATSUMOTO, ISOLATION OF TWO NEW RELATED PEPTIDE ANTIBIOTICS, CEREXINS A AND B The Journal of Antibiotics. ,vol. 28, pp. 56- 59 ,(1975) , 10.7164/ANTIBIOTICS.28.56
Y. Fujita, J. Kollonitsch, B. Witkop, THE STEREOSPECIFIC SYNTHESIS OF THREO-GAMMA-HYDROXYHOMO-L-ARGININE FROM LATHYRUS SPECIES. Journal of the American Chemical Society. ,vol. 87, pp. 2030- 2033 ,(1965) , 10.1021/JA01087A030