29 – Paroxysmal Dyskinesia

摘要: Paroxysmal dyskinesias comprise a heterogenous group of disorders that share the recurrence sudden abnormal involuntary movements out normal background. The may be choreic, ballistic, or dystonic but are more frequently combination these, thus giving strong support to use term dyskinesia account for this complexity. episodes last few seconds several hours and purely motor-oriented, without alteration in consciousness. Recovery from attacks is usually rapid complete. This chapter deals separately with each subtype paroxysmal dyskinesia, because etiologies presumed pathophysiology appear substantially different. Despite advances, important details remain unknown. Progress gene identification understanding link between mutated product probable transient ion channel dysfunction becoming key targets investigation. However, it already possible formulate various hypotheses can tested promote general perspective disorder.