Attempts to improve strain A-101 of Yarrowia lipolytica for citric acid production from n-paraffins
作者： M. Wojtatowicz , G.L. Marchin , L.E. Erickson
DOI: 10.1016/0032-9592(93)85028-E
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摘要: Abstract Citric and isocitric acid production were measured in strain A-101 of Yarrowia lipolytica . Product yield on n-hexadecane, including substrate used for cell growth, was the range 1·08–1·44 g total acid/g n-hexadecane. The citric fraction acids synthesized by a particular subculture 54–64%. Mutants Y. incapable growth citrate isolated at low frequency extremely unstable. difficulty due to ploidy our as confirmed determination nuclear DNA content, average diameter, UV inactivation kinetics. Some mutants also that excreted predominantly when grown
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sci-hub.se 参考文章(20)
John M. Lowenstein, [66] Chemical methods for citrate and aconitate Citric Acid Cycle. ,vol. 13, pp. 513- 516 ,(1969) , 10.1016/0076-6879(69)13073-6
Gerald R. Fink, [3] The biochemical genetics of yeast Methods in Enzymology. ,vol. 17, pp. 59- 78 ,(1970) , 10.1016/0076-6879(71)17167-4
T Suzuki, S Nishibayashi, T Kanbe, T Kuroiwa, K Tanaka, Variance of ploidy in Candida albicans. Journal of Bacteriology. ,vol. 152, pp. 893- 896 ,(1982) , 10.1128/JB.152.2.893-896.1982
M Matsuoka, Y Ueda, S Aiba, Role and control of isocitrate lyase in Candida lipolytica. Journal of Bacteriology. ,vol. 144, pp. 692- 697 ,(1980) , 10.1128/JB.144.2.692-697.1980
K. Burton, A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid Biochemical Journal. ,vol. 62, pp. 315- 323 ,(1956) , 10.1042/BJ0620315
R Poulter, M G Shepherd, K Jeffery, V Hanrahan, D Markie, P A Sullivan, Recombination analysis of naturally diploid Candida albicans. Journal of Bacteriology. ,vol. 152, pp. 969- 975 ,(1982) , 10.1128/JB.152.3.969-975.1982
Claude M. Gaillardin, V�ronique Charoy, Henri Heslot, A study of copulation, sporulation and meiotic segregation in Candida lipolytica Archiv f�r Mikrobiologie. ,vol. 92, pp. 69- 83 ,(1973) , 10.1007/BF00409513
Shuichi Aiba, Masayoshi Matsuoka, Citrate production from n-alkane by Candida lipolytica in reference to carbon fluxes in vivo European Journal of Applied Microbiology and Biotechnology. ,vol. 5, pp. 247- 261 ,(1978) , 10.1007/BF00504713
MING CHUNG CHANG, HAT KWAN JUNG, TAKAHITO SUZUKI, MASAMICHI TAKAGI, KEIJI YANO, None, Ploidy in the asporogenous yeast Candida maltosa, isolation of its auxotrophic mutants and their cell fusion. Journal of General and Applied Microbiology. ,vol. 30, pp. 489- 497 ,(1984) , 10.2323/JGAM.30.489
Lyferd J Wickerham, Cletus P Kurtzman, Alberta I Herman, None, Sexual reproduction in Candida lipolytica. Science. ,vol. 167, pp. 1141- 1141 ,(1970) , 10.1126/SCIENCE.167.3921.1141