Properties of cytochrome P450 isoenzymes and their substrates Part 2: properties of cytochrome P450 substrates
作者： Dennis A. Smith , Mark J. Ackland , Barry C. Jones
DOI: 10.1016/S1359-6446(97)01085-4
关键词:
摘要: Cytochrome P450 isoenzymes are pivotal in drug clearance. Part 1 of this two-part review, published the October issue Drug Discovery Today , described active site characteristics members superfamily. This article describes great increase our understanding substrate requirements human cytochrome family and highlights relevance knowledge for design new therapeutic agents.
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