摘要: Despite the first recognition of red cells in blood by Dutch scientist Jan Swammerdam around 1658 and description shape erythrocytes his acquaintance Antoni van Leeuwenhoek 1695, colorless cellular component remained unrecognized until 1843. At this time “white globules” were identified simultaneously Gabriel Andral William Addison (working France Scotland, respectively) shown to be associated with disease. Addison, for instance, recognized pus as being that had passed out circulation site infection [1].