Rapamycin promotes the osteoblastic differentiation of human embryonic stem cells by blocking the mTOR pathway and stimulating the BMP/Smad pathway.
作者： Kyu-Won Lee , Jin-Yong Yook , Mi-Young Son , Min-Jeong Kim , Deog-Bon Koo
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摘要: Studies revealed that PI3K/AKT/mTOR signaling is important in the regulation of human embryonic stem cell (hESC) self-renewal and differentiation. However, its action on osteogenic …
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