作者: Matti Kiupel , Danielle R. Desjardins , Ailam Lim , Carole Bolin , Cathy A. Johnson-Delaney
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摘要: We report an outbreak of severe respiratory disease associated with a novel Mycoplasma species in ferrets. During 2009–2012, characterized by nonproductive coughing affected ≈8,000 ferrets, 6–8 weeks age, which had been imported from breeding facility Canada. Almost 95% became ill, but almost none died. Treatments temporarily decreased all clinical signs except cough. Postmortem examinations euthanized ferrets revealed bronchointerstitial pneumonia prominent hyperplasia bronchiole-associated lymphoid tissue. Immunohistochemical analysis polyclonal antibody against bovis demonstrated intense staining along the bronchiolar brush border. Bronchoalveolar lavage samples 12 yielded fast-growing, glucose-fermenting mycoplasmas. Nucleic acid sequence PCR-derived amplicons portions 16S rDNA and RNA polymerase B genes failed to identify mycoplasmas showed that they were most similar M. molare lagogenitalium. These findings indicate causal association between newly recognized pulmonary disease.