Strategies to Regulate Myopia Progression With Contact Lenses: A Review

摘要: Purpose: Higher myopic refractive errors are associated with serious ocular complications that can put visual function at risk. There is respective interest in slowing and if possible stopping myopia progression before it reaches a level increased risk of secondary pathology. The purpose this report was to review our understanding the rationale(s) success contact lenses (CLs) used reduce progression. Methods: A commenced by searching PubMed database. inclusion criteria stipulated publications clinical trials evaluating efficacy CLs regulating based on primary endpoint changes axial length measurements published peerreviewed journals. Other from conference proceedings or patents were exceptionally considered when no peer-review articles available. Results: mechanisms presently support regulation change relative peripheral defocus changing foveal image quality signal potentially interfere accommodative system. Ten addressing reviewed, including corneal therapy (orthokeratology), gradient lenses, bifocal (dual-focus) multifocal lenses. Conclusions: reported be well accepted, consistent, safe methods address children. Corneal (orthokeratology) so far method largest demonstrated across different ethnic groups. However, factors such as patient convenience, degree initial myopia, non-CL treatments may also considered. combination strategies (i.e., central defocus, spectral filters, pharmaceutical delivery, active lens-borne illumination) single device will present further testable hypotheses exploring how reinforce compete each other improve CLs.